Brain probes could help alzheimer patients

One of the most lucrative markets these days is for anything that help people lose weight, and much of that research is in the field of appetite suppression – and there is a large pot of gold for anyone who finds one with no side effects. However, a startling by product of such research being done at Toronto Western Hospital in Ontario, Canada, has accidentally discovered a way to trigger vivid memories.

The hero of the piece is an obese man who had volunteered to help scientists as they attempt to find a part of the brain that could suppress the appetite when stimulated electrically.

When the scientists stimulated the hypothalamus, which has been associated with hunger, the man suddenly experienced a vivid memory from 30 years before. It was complete in all details, the people, the place, the colours exactly as if he were back there. While the hypothalamus has not previously been associated with memory, it borders a part of the brain that is known to influence memory and emotion so it seemed like a logical area to explore.

The researchers then implanted a device in his brain that would constantly stimulate that section of the hypothalamus. The device is similar to ones that have been implanted in other parts of the brain to control tremor in Parkinson’s disease.

After three weeks of stimulation at a low level, the man’s performance on two memory tests improved significantly and this leads researchers to hope that they can develop the technique into a treatment for Alzheimer’s disease. They are now testing the device to see if it can stem the memory loss that can be such a distressing part of Alzheimer’s disease.

Want to boost your IQ

Exercise is the keystone for healthy living, but it is not often advocated to help you to boost your IQ. We already know that older people who exercise three or more times a week have a significantly reduced risk of developing Alzheimer’s and other types of dementia. Whatever your age, if you exercise regularly you have a 30 to 40 percent lower risk of dementia, and even as little as 15 minutes of exercise, three days a week, cuts your risk significantly. One short, brisk, walk every day can make a real difference, but what is new is that recent studies have shown that some forms of exercise may actually help you think better, while others have little or no impact on your brain matter. Here’s three suggestions for what works, and what doesn’t, for those ‘little grey cells’.

Aerobic Training:
In 2006, Arthur Kramer of the University of Illinois used MRIs to prove that aerobic exercise builds grey and white matter in the brains of older adults. Later studies found that more aerobically fit schoolkids also perform better on cognitive tests. Widely accepted now that aerobic exercise is one of the best things you can do to stay mentally agile into old age.
Impact on intelligence: STRONG

Weight Training:
It might make you feel good to have ripped muscles, but researchers have found only the most tenuous link between heavy resistance training and improved cognitive function.
Impact on intelligence: NEGLIBIBLE

Yoga:
You need as much oxygen as you can get, particularly for brain function, but under stress we tend to hold our breath and reduce our intake which can certainly affect our memory. Yoga can break that habit by helping you learn to breathe correctly which results in less stress and more oxygen.
Impact on intelligence: POSSIBLY STRONG

Juice benefits for Alzheimer’s

A recently concluded study which investigated Alzheimer’s disease in older Japanese populations living in Japan, Hawaii and Seattle, has found that people who drank fruit and vegetable juices more than three times a week had a 76 percent lower risk of developing Alzheimer’s disease than those who drank juice less than once per week.

This ten-year study was based on the fact that there is a very low incidence rate of Alzheimer’s disease in the Japanese population in their native country, but when Japanese people in the USA were studied they were found to have almost the same incidence rates as Americans have. Obviously this indicates that environmental factors like diet and lifestyle are important contributors to disease risk, but that the benefit of drinking juice was most apparent in those people who carry the genetic marker linked to late-onset Alzheimer’s disease — the most common form of the disease, which typically occurs after the age of 65.

Further research is being done on exactly what types of juice that would bring most benefit but from a natural healing viewpoint the most likely would seem to be pomegranate, cherry, red grape juice, red wine and fresh juiced vegetables. The researchers say that their findings are not yet conclusive so cannot be guaranteed to prevent Alzheimer’s but common sense would indicate that freshly juiced fruit and vegetables have all their essential minerals, vitamins and enzymes and would certainly improve overall health generally if not Alzheimer’s specifically.

Another benefit for coffee?

If you really enjoy your coffee, and have a high fat diet, then despite kind friends like me warning you of potential health problems, there is some new research that might cheer you up. It was reported by Jonathan D. Geiger, Ph.D., of the University of North Dakota, in the April issue of the Journal of Neuroinf – lammation, that animal tests appeared to protect the blood-brain barrier from cholesterol-induced damage in rabbits. Why is this important? Because high levels of cholesterol are a risk factor for Alzheimer’s disease, perhaps by compromising the protective nature of the blood-brain barrier. Other experimental studies have suggested that caffeine has beneficial effects for a number of neurovascular disorders, including Alzheimers’ but it is not yet conclusive. So I sugest you go easy on the high fat cappuccino’s for a while yet.

Blood Test for Alzheimer’s diagnosis?

18 million people worldwide are affected by Alzheimer’s, but it has been hard for doctors to make an accurate diagnosis until the disease is well progressed. Now, researchers have developed a simple blood test that may be able to predict whether mild lapses of memory could be an early sign of Alzheimer’s disease. In a study published in the journal Nature Medicine, an international team of researchers describe 18 cell-signalling, or communication, proteins found in blood that predicted with 90 percent accuracy whether a person would develop Alzheimer’s disease.

Currently, doctors diagnose Alzheimer’s disease by excluding other potential causes of memory loss, such as stroke, tumours and heavy drinking. They can also administer simple paper-and-pencil tests, and sometimes use brain scans, but this blood test could be used to detect changes in these proteins and because they occur early on in the disease process they could be used to predict the disease two to six years ahead of its onset.

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